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Pascoe - Legapas Oral Drops

Pascoe - Legapas Oral Drops

Regular price
$17.45
Sale price
$17.45

Info: 45 ml Bottle with an Orifice Reducer to Dispense as Drops (a 30 to 50 Day Supply)

Sometimes we may get plugged up and just need a short-term laxative to get relief from occasional constipation. Legapas is made from the bark of Cascara sagrada – a shrub indigenous North Americans have been using to cleanse the bowels for hundreds of years, which has also been incorporated into Western medicine since the late 1800s. It comes here in the form of a tincture which you just mix into a bit of hot water, which many prefer over having to choke down some pills.

Info: 45 ml Bottle with an Orifice Reducer to Dispense as Drops (a 30 to 50 Day Supply)

Sometimes we may get plugged up and just need a short-term laxative to get relief from occasional constipation. Legapas is made from the bark of Cascara sagrada – a shrub indigenous North Americans have been using to cleanse the bowels for hundreds of years, which has also been incorporated into Western medicine since the late 1800s. It comes here in the form of a tincture which you just mix into a bit of hot water, which many prefer over having to choke down some pills.

Product Notes:

Cascara sagrada has not just one but two principal mechanisms of action to relieve constipation, which make it quite effective and well-tolerated in the short-term but can backfire if not used as directed.

First and foremost, it is what's known as a stimulant laxative, which acts directly on the colon or large intestine to promote the bowel movements that organ is responsible for, by stimulating the nerves in its walls to cause contractions. As such, it should only be used for a short period of time – for no more than 7 days in a row – otherwise, not only can a tolerance develop, but the colon's muscles might not work normally without it.

Second, it makes the actual stools easier to move, by increasing their water content, thanks to some compounds called anthraquinones that they (along with aloe, rhubarb, and senna) contain, which slow down how much water and electrolytes the large intestine absorbs from the stuff passing through it. This not only makes the stools less hard and lumpy and painful to pass, but also increase their volume, which increases how much pressure they places on the colon's walls, which is the normal means of stimulating its muscle contractions to evacuate the contents. The danger here is, again, you don't want to overdo it, because it can lead to electrolyte and fluid imbalances that can have side effects like the ones listed below.

Ingredients:

Each 1 g (= 33 drops - a typical dose) contains:
Fluid extract (1:1.0-1.2) of 500 mg Cascara sagrada - Frangula purshiana (D.C.) (bark, aged), standardized to 20 mg of hydroxyanthracene glycosides calculated as Cascaroside A.

Non-medicinal ingredients: Purified Water and Alcohol; contains 23% (V/V) alcohol.

Suggested Usage:

Quantity: Adults and children 12 years old and up: Take between 30 and 50 drops once a day in half a cup of either warm or hot water, either in the mornings or the evenings. (That quantity weighs between 0.9 and 1.5 grams, so if you have an accurate kitchen scale, you can either use its 'tare' feature to add the desired amount of Legaspas to an empty pre-weighed cup, or add it gradually to the cup of hot water on the scale.) Do not use within 2 hours of taking other medicines, to prevent interfering with their function.

Duration of use: Do not use for more than 7 consecutive days.

Direction of use: Allow 6 to 12 hours for laxative effect to occur. The maximum daily dose must not exceed 50 drops. The appropriate dose for a given person is the lowest dose needed for soft, formed stools.

Warnings:

Keep out of reach of children. Do not use if you are pregnant or breastfeeding; or if you are taking thiazide diuretics, corticosteroids, licorice root, or other drugs that may aggravate electrolyte imbalance; or if you are experiencing abdominal pain, nausea, fever, vomiting, hemorrhoids.

Use with caution if you have a kidney disorder or are taking heart medications. Reduce dose or discontinue use if abdominal cramps, spasms, and/or pain occur.

Potential side effects: Very rarely cramp-like gastrointestinal symptoms; in these cases, the dose will have to be reduced. Harmless discoloration of the urine may occur. Prolonged use or using at higher than recommended doses may cause disturbances of the water and electrolyte balance. If that results in diarrhea, it may lead to the loss of potassium, which may give rise to disorders of heart function and muscle weakness, especially if cardiac glycosides (drugs that strengthen the heart muscle), diuretics (drugs that increase urinary output), and/or cortisone and cortisone-like drugs (adrenal cortical steroids) are being taken at the same time. Prolonged use may lead to excretion of protein and blood in the urine. Patients may also experience discoloration of the intestinal mucosa (pseudomelanosis coli), which usually resolves upon discontinuation of the product.

Drug Interactions: As noted above, chronic use or abuse may lead to potassium deficiency and thus increase the effects of certain drugs that strengthen the heart muscle (cardiac glycosides) and interfere with the effects of drugs for heart rhythm disturbances (antiarrhythmics). Potassium loss may be increased by the concomitant use of certain drugs that increase urinary output (diuretics), cortisone and cortisone-like drugs (corticosteroids) or licorice root.

Health Canada Natural Product Number: 80002081.

UPC / Barcode: 4039343090207