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bottle of NOW UC-II
diagram of how UC-II works

NOW - UC-II (Undenatured Collagen)

Regular price
$50.61
Sale price
$50.61

Info: 60 Veg. Capsules

UC-II is an un-denatured or native Type II Collagen whose efficacy has been demonstrated in human clinical studies, and has been enhanced with a natural source of calcium and over 70 trace minerals sourced from red algae from the pristine waters of Iceland, which has also shown some promise in relieving arthritic pain.

Info: 60 Veg. Capsules

UC-II is an un-denatured or native Type II Collagen whose efficacy has been demonstrated in human clinical studies, and has been enhanced with a natural source of calcium and over 70 trace minerals sourced from red algae from the pristine waters of Iceland, which has also shown some promise in relieving arthritic pain.

Product Notes:

Derived from the cartilage from chicken sternums, this source of collagen supports healthy joints and promotes mobility and flexibility by working with the immune system to retain and restore cartilage.

Our synovial joints (ankles, knees, hips, shoulders, elbows, wrists, and fingers and toes) and several other body parts contain hyaline cartilage to act as a shock absorber and help prevent them from binding up, which is mainly composed by Type II collagen (a type of protein).

That cartilage can be subjected to a lot of wear and tear by engaging in sports or other activities, and we may also naturally produce less of it as we age - which is where supplements figure in. But not UC 2 collagen supplements are created equal: some have been denatured, meaning they were "hydrolyzed" or broken down by using chemicals or high temperatures when they were processed, which can make them much less effective. And this particular type has been shown to work well with our body's own processes for breaking down collagen into its components naturally, to liberate a specific type of peptide or cluster of amino acids that's particularly adept at cleaning out worn out joint tissue.

NOW UC-II Ingredients:

Each capsule contains:

- 10 mg Undenatured Type II Collagen (from 40 mg UC-II® Standardized Chicken Cartilage)

250 mg Mineralized Red Algae (as Aquamin®) (Lithothamnium corallioides) (Whole plant), providing: 80 mg of Calcium and 6.25 mg of Magnesium.

Non-medicinal ingredients: Veg. capsule (hypromellose. water), Cellulose, Stearic Acid (vegetable source), Silica.

Suggested Usage:

Adults: Take 1 capsule daily with meals. If taking other medication, take this either a few hours before or after. Consult a healthcare practitioner for use beyond 12 weeks. Store in a cool, dry place.

Warnings:

Consult a healthcare practitioner prior to using UCII if you are pregnant or breastfeeding. Consult a healthcare practitioner if symptoms persist or worsen whiles using.

Health Canada Natural Product Number: 80041515.

Supporting Science:

Regarding UC-II®

Not only has this particular type of UC-II been shown to be effective in treating arthritis, but research published in the International Journal of Medical Sciences also confirmed that for some individuals, taking 40 mg of UC II daily is twice as effective as 1500 mg of glucosamine and 1200 mg of chondroitin.

Crowley DC, et al. “UC-II® Shown to Support Joint Mobility, Flexibility and Comfort in a Randomized Double-Blind Study.” International Journal of Medical Sciences, 2009.

Zhang, Ling-Ling et al. “A randomized, double-blind, multicenter, controlled clinical trial of chicken type II collagen in patients with rheumatoid arthritis.” Arthritis & Rheumatology, 2008.

It can also reduce knee pain caused by over-exertion and improve joint flexibility even among those without arthritis:

Lugo, James P et al. “Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers.” Journal of the International Society of Sports Nutrition, 2013.

Knaub, Katharina et al. “UC-II® Undenatured Type II Collagen Reduces Knee Joint Discomfort and Improves Mobility in Healthy Subjects: A Randomized, Double- Blind, Placebo-Controlled Clinical Study.” Journal of Clinical Trials, 2022.

Schön, Christiane et al. “UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study.” Journal of Integrative and Complementary Medicine, 2022.

Regarding Aquamin:

Frestedt, Joy L et al. “A natural seaweed derived mineral supplement (Aquamin F) for knee osteoarthritis: a randomised, placebo controlled pilot study.” Nutrition Journal, 2009.

UPC / Barcode: 733739831347