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AOR P.E.A Activate capsules
AOR P.E.A Activate lozenges

AOR - PEA Activate (Palmitoylethanolamide)

Regular price
$39.95
Sale price
$39.95

Info: Available in 90 Capsules (400mg) or 60 Lozenges (600mg)

New! The first P.E.A. supplement licensed in Canada designed to help relieve chronic pain and inflammation. Available in two formats and strengths, for the same net amount per day (since you either take three capsules or two lozenges per day). 

Info: Available in 90 Capsules (400mg) or 60 Lozenges (600mg)

New! The first P.E.A. supplement licensed in Canada designed to help relieve chronic pain and inflammation. Available in two formats and strengths, for the same net amount per day (since you either take three capsules or two lozenges per day). 

Product Notes:

The Multiple Target Molecule - A Key Player in the Endocannabinoid System

A unique fatty acid that can be found in eggs and a variety of plant sources, and which is also produced endogenously (within our own bodies), Palmitoyl-ethanol-amide (PEA) plays an important role in the body's systematic response to pain and inflammation within the Endocannabinoid System.

Palmitoylethanolamide (P.E.A) is an endocannabinoid-like molecule which our bodies produce as needed to deal with bodily stress, injury, or infection. It serves as part of Endocannabinoid System (ECS): a complex communication network or cell-signaling system throughout our bodies which helps regulate a variety of functions, including protecting nerve cells, preventing arthritis and cardiovascular disease, and countering inflammation.

Is PEA a cannabinoid?

Although P.E.A itself shares many of the same functions as the phytocannabinoids in CBD (which is derived from cannabis oil), it is produced naturally by most mammals, so it receives a different medical and legal classification.

Some common food sources of PEA include milk, peas, tomatoes, corn, soybeans, soy lecithin, and peanuts. This supplementary form developed by Advanced Orthomolecular Research is chemically identical [N-(2-Hydroxyethyl)hexadecanamide] to the natural mammalian form, and is derived from Malaysian palm oil, ethically sourced from one of the only certified and guaranteed sustainable producers in the world.

The effectiveness of Advanced P.E.A. has been demonstrated in multiple clinical studies which have shown that 600 mg every day for three weeks significantly improved the comfort and quality of life of 636 patients.

P.E.A and Pain

A 2017 meta-analysis investigated the efficacy of P.E.A for pain relief. Eight randomized controlled trials accounting for 743 patients receiving PEA and 460 patients given either placebo or no treatment showed a significantly greater pain reduction in those given PEA. Daily dosages ranged from 300mg to 1200mg, and treatment duration ranged from 10 to 180 days. Interestingly, there was no association between longer treatment durations and pain efficacy.

The authors found one trial that compared 2 weeks of use of P.E.A. versus ibuprofen in 24 patients with arthritis of the TMJ (temporomandibular joint). Patients given PEA has significantly decreased pain compared to those given ibuprofen. Ibuprofen treatment also resulted in 3 patients to have the side effect of a stomach ache, compared the PEA group which reported no side effects.

PEA products available in other markets including peaCURE, OptiPEA, Mirica, Normast, Pelvilenand, and PEApure are not currently licensed for sale in Canada. AOR PEA Active is the first Palmitoylethanolamide product to be issued a Health Canada Natural Product Number (NPN): 80090272 (capsules) or 80090258 (lozenges).

Related Reading: Improving Health by Reducing InflammationNatural Solutions for Tendonitis and Inflammation

Supporting Science:

Study: "Efficacy of Palmitoylethanolamide for Pain: A Meta-Analysis." Pain Physician. 2017 Jul.

Other research has examined PEA use for neuroinflammation, Type II diabetic neuropathy, providing analgesia and neuroprotection related to chemotherapy, as well as immune system support for upper respiratory tract infections. E.g., see "Micronized palmitoylethanolamide reduces the symptoms of neuropathic pain in diabetic patients." Pain Res Treat. 2014.

P.E.A Activate Ingredients:

400 mg Palmitoylethanolamide (P.E.A)* per capsule, micronized; or,

600 mg per Lozenge, from a Genuine Italian source.

Non-medicinal ingredients:

PEA capsules contain no non-medicinal ingredients except for hypromellose (the capsule itself).

PEA lozenges contain ascorbyl palmitate, isomalt, natural watermelon flavour, maltodextrin, modified food starch, xanthan gum, monk fruit extract, hydroxypropyl cellulose, and microcrystalline cellulose. 

Vegan. Non-GMO. Gluten-free. Also contains no: wheat, corn, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish, or animal byproducts.

Suggested Usage:

PEA Capsules: Adults: Take 1 capsule 3 times daily, either with or without food, or as directed by a healthcare practitioner. 

PEA Lozenges: Adults: Chew, dissolve, or swallow one lozenge two times a day, either with or without food, or as directed by a healthcare practitioner.

Consult your healthcare practitioner for use beyond 40 days.

Warnings:

Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding. Consult a healthcare practitioner if symptoms persist or worsen.

PEA side effects/contraindications: none listed.


Product Options:
90 Capsules (400mg each) - $39.95 - UPC: 624917044225
60 Lozenges (600mg each) - $39.95 - UPC: 624917044218