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Douglas Laboratories DIM Enhanced
BioResponse DIM absorption rates

Douglas Laboratories - DIM Enhanced

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Info: 30 Vegetarian Capsules

This item is temporarily unavailable from the manufacturer, likely until April, 2025. Please see DIM & Detox by Pure Encapsulations.

Looking for a way to promote a healthy estrogen metabolism, or to reduce the severity and duration of symptoms associated with recurrent breast pain (cyclical mastalgia), or to enhance your body's natural detoxification process? DIM Enhanced provides a quartet of plant-based ingredients that support healthy hormone balance and immune health.

Product Notes:

DIM Enhanced Helps Promote Healthy Estrogen Balance

DIM (Diindolylmethane) is a molecule with demonstrated ability to stimulate the action of detoxification enzymes in the body as well as support normal hormone metabolism; this formulation uses a proprietary form of it that's been micro-encapsulated to make it far more absorbable than other types. Curcumin, the active compound in Turmeric, helps reduce inflammation. The antioxidant capacity of green tea supports immune function, heart health, and hormone detoxification. Finally, Wasabi contains long chain isothiocyanates (ITCs) whose detoxification capacity is 10 to 25 times more powerful than the ITCs in other cruciferous vegetables.

DIM Enhanced Ingredients:

Each capsule contains:

125 mg BioResponse DIM®, providing:
- 3,3-Diindolylmethane: 31.25 mg
- Green Tea Leaf Extract (Camellia sinensis) (20:1) (4000 mg dried equivalent; 95% Polyphenols, 45% EGCG [epigallocatechin-3-gallate]): 200 mg

125 mg MERIVA®, providing:
- Curcuminoids (from Curcuma longa rhizome): 25 mg
- Wasabi Rhizome (Wasabia japonica): 50 mg

Non-medicinal ingredients: Hypromellose (capsule), cellulose, silica, magnesium stearate, dibasic calcium phosphate dihydrate, starch, vitamin E, phosphatidylchloline (from sunflower).

BioResponse DIM® is a trademark of BioResponse, L.L.C., Boulder, CO. Meriva® is a registered trademark of Indena S.p.A, Milano.

Suggested Usage:

Adults: Take 1 capsule 1 or 2 times per day with food, or as directed by a healthcare practitioner. Consult a healthcare practitioner for use beyond 12 weeks. Store in a cool, dry place.


Do not use if you are pregnant or breastfeeding. Consult a health care practitioner prior to using Douglas Labs DIM Enhanced if you are taking any medication or natural health products, if you have symptoms of low estrogen (such as joint pain, mood changes, changes in libido, hot flashes, night sweats, vaginal dryness or irregular menstruations), if you have an iron deficiency, if you have gallstones or a bile duct obstruction, if you have stomach ulcers or excess stomach acid, or if you are attempting to conceive.

To exclude the diagnosis of a serious cause of hormonal imbalance, consult a health care practitioner prior to use. If you develop symptoms of low estrogen, discontinue use and consult a health care practitioner. If you have a liver disorder, consult a health care practitioner prior to use. Stop use if you develop symptoms of liver trouble such as yellowing of the skin/eyes (jaundice), stomach pain, dark urine, sweating, nausea, unusual tiredness and/or loss of appetite and consult a health care practitioner. Rare, unpredictable cases of liver injury associated with green tea extract-containing products have been reported.

Health Canada Natural Product Number: 80064554.

Supporting Science:

Bradlow, H Leon. “Review. Indole-3-carbinol as a chemoprotective agent in breast and prostate cancer.” In Vivo (Athens, Greece), 2008.

Dalessandri, Kathie M et al. “Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer.” Nutrition and Cancer, 2004.

Higdon, Jane V et al. “Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.” Pharmacological Research, 2007.

Lee, Geum-A et al. “Inhibitory effects of 3,3'-diindolylmethane on epithelial-mesenchymal transition induced by endocrine disrupting chemicals in cellular and xenograft mouse models of breast cancer.” Food and Chemical Toxicology, 2017.

Thomson, Cynthia A et al. “A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen.” Breast Cancer Research and Treatment, 2017.

Thomson, Cynthia A et al. “Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies.” Nutrition Reviews, 2016.

UPC / Barcode: 310539979532