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Douglas Laboratories - Relora-Plex

Douglas Laboratories - Relora-Plex

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Info: 60 Vegetarian Capsules

This item is temporarily unavailable from Douglas Labs until Summer 2025. Alternatively, please see Protocol Adrenal Cortisol Support

Relora-Plex is a unique blend of several types of B vitamins with two traditional herbal medicine extracts (backed by research) designed to help us feel less stress and temporarily relieve the symptoms of perceived stress without causing drowsiness throughout the day.

Product Notes:

When we experience stress, we secrete more cortisol, which triggers producing lots of glucose to serve almost exclusively as energy for our brains' hyperactive 'fight or flight' response, at the expense of other tissues which would use it for normal functions like digestion, the immune system, and producing other hormones (like the ones which help us relax).

The combination of Magnolia officinalis and Phellodendron amurense has been shown to have positive results in randomized clinical trials in such factors as reducing anxiety in temporary, transitory anxiety in premenopausal women, in one study; or in improving the vigor and reducing the sleep disturbances, fatigue, restlessness, tension and feelings attributed to stress compared to the control group in another study, and in improving mood and reducing anger, depression, and confusion, as well. And in a 2013 study of 56 moderately stressed men and women between the ages  17 and 39, they found reductions in Overall Stress (an 11% decrease, with the measure they used), Tension (-13%), Depression (-20%), Anger (-42%), Fatigue (-31%), and Confusion (-27%), and improved Global Mood State (+11%) and Vigor (+18%).

Relora-Plex Ingredients:

Each capsule contains:

Riboflavin: 5 mg
Niacinamide: 5 mg
Thiamine (thiamine mononitrate): 4.5 mg
Vitamin B6 (pyridoxine hydrochloride): 4 mg
Folic Acid: 100 mcg
Vitamin B12 (cyanocobalamin): 50 mcg
Relora®: 250 mg, providing:
- Huo po (Magnolia officinalis) stem bark (8.5 % honokiol): 68.75 mg
- Phellodendron (Phellodendron amurense): (2.5 % berberine): 22.5 mg

Non-medicinal ingredients: Hypromellose, Cellulose, Magnesium Stearate, Pregelatinized Starch, Corn Starch, Silica.

Relora is a trademark of Next Pharmaceuticals Inc.

Suggested Usage:

Adults: Take 1 capsule three times daily, or as directed by your healthcare practitioner. Consult your healthcare practitioner for use beyond 6 weeks.


Do not use if you are pregnant or breastfeeding. Consumption with alcohol, other medications or natural health products with sedative and/or analgesic properties is not recommended. Consult a healthcare practitioner prior to using Douglas Labs Relora-Plex if you are taking any prescription medication, if you have a kidney disorder, or if you have blood pressure problems, or if you suffer from any psychological disorder and/or condition such as frequent anxiety or depression. Concomitant use with herbs, supplements and medications that have sedative properties might increase the risk of excessive drowsiness.

Consult a health care practitioner if symptoms persist or worsen. May cause heartburn, shaking hands, perilabial numbness, sexual dysfunction and thyroid dysfunction. Some people may experience drowsiness; exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness.

Health Canada Natural Product Number: 80028378.

ReloraPlex Supporting Science:

“Effect of Magnolia officinalis and Phellodendron amurense (Relora®) on cortisol and psychological mood state in moderately stressed subjects.” Journal of the International Society of Sports Nutrition, Aug. 2013.

"Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women: a pilot, double-blind, placebo-controlled clinical trial." Nutrition Journal. Apr. 2008.

"Anxiolytic properties of botanical extracts in the chick social separation-stress procedure." Psychopharmacology (Berl).  Jan. 2001.

UPC / Barcode: 310539021361