Info: Available in 60 or 180 Veg. Capsules (500mg)
Most people were told to eat their broccoli growing up, and for good reason! Broccoli supports general good health, and just as importantly, it stimulates the production of Sulforaphane, a substance which has many health benefits.
Eating enough broccoli every day to obtain a therapeutic level of Sulforaphane is neither a practical nor appealing culinary delight. But, good news - as BroccoGen 10 is now available and has been formulated from a non-GMO source that's been specially bred to have over 100 times more Sulforaphane Glucosinolate (SG) than is usually found in broccoli.
Ingredients:Each capsule contains:
500 mg Broccoli Sprout Extract (Brassica oleracea italica) (15 mg Sulforaphane Glucosinolate)
Non-medicinal ingredients: Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate, Hypromellose and Water.
Contains no artificial color, sweeteners, soy, yeast, wheat, gluten, corn, milk, eggs, shellfish or preservatives.
Suggested Usage:Adults: Take 2 to 4 capsules three times per day with a meal, or as directed by your healthcare practitioner. Sulforaphane is chemoprotective. Consult your healthcare practitioner for use beyond 2 weeks. Store under normal conditions.
Warnings:Keep out of reach of children. Do not use if pregnant or breastfeeding. Consult a healthcare practitioner prior to use if you are taking blood thinners, or for use beyond 2 weeks.
Health Canada Natural Product Number: 80028444.
Sulforaphane Glucosinolate (SG) has many health benefits such as reducing the risk of cardiovascular disease (ref. 1), protecting the body from radiation(2), free radicals, oxidative stress, and inflammation (3), as well as providing neuroprotection (4). In addition, SG may aid in supporting breast and prostate health (5), the immune system (6), and brain function (4). Currently the anti-cancer properties of SG are being extensively studied (5,7,8). Interestingly, SG was also recently shown to have beneficial effects on autistic spectrum disorders (9) and is currently under clinical trial as a novel treatment (10).
1. Bai, Y. et al. "Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation." Oxid Med Cell Longev. 2015;2015:407580. doi: 10.1155/2015/407580.
2. Katoch O, Kumar A, Adhikari JS, Dwarakanath BS, Agrawala PK. "Sulforaphane mitigates genotoxicity induced by radiation and anticancer drugs in human lymphocytes." Mutat Res. 2013 Dec 12;758(1-2):29-34. PMID: 24004877
3. Greaney AJ, Maier NK, Leppla SH, Moayeri M. "Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism." J Leukoc Biol. 2016 Jan;99(1):189-99. PMID: 26269198
4. Wang G, et al. "Sulforaphane Prevents Neuronal Apoptosis and Memory Impairment in Diabetic Rats." Cell Physiol Biochem. 2016;39(3):901-7. PMID: 27497670
5. Atwell LL, et al. Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention. Curr Pharmacol Rep. 2015 Apr 1;1(2):102-111. PMID: 26042194
6.Kim HJ, Barajas B, Wang M, Nel AE. "Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells." J Allergy Clin Immunol. 2008 May;121(5):1255-1261.e7. PMID: 18325578
7. Li Y, Zhang T. "Targeting cancer stem cells with sulforaphane, a dietary component from broccoli and broccoli sprouts." Future Oncol. 2013 Aug;9(8):1097-103. PMID: 23902242
8. Ganai SA. "Histone deacetylase inhibitor sulforaphane: The phytochemical with vibrant activity against prostate cancer." Biomed Pharmacother. 2016 Jul;81:250-7. PMID: 27261601
9. Singh K, et al. "Sulforaphane treatment of autism spectrum disorder (ASD)." Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15550-5. PMID: 25313065
10. "Sulforaphane Treatment of Children With Autism Spectrum Disorder (ASD)". clinicaltrials.gov. Retrieved 3 May 2016.