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NOW OralBiotic (BLIS K12 Probiotic)

NOW - OralBiotic (BLIS K12 Probiotic)

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Info: 60 Lozenges

OralBiotic is temporarily unavailable from the manufacturer. Please see CulturedCare Probiotic Gum which contains the same BLIS K12 ingredient.

These probiotic lozenges from NOW contain Streptococcus salivarius BLIS K12, a proprietary strain of a naturally occurring microorganism which has been clinically shown to support both oral and throat health, which was first identified, isolated, and studied in New Zealand.

Product Notes:

NOW OralBiotic works by colonizing the oral cavity with BLIS K12 (aided by the inclusion of the prebiotic FOS to provide nutritional support for it). This beneficial bacteria crowds out other bacteria which may have been proliferating and causing a range of issues, including painful gums, a white build up on the tongue, ear aches/infections (otitis media), cavities (dental caries), strep throat (streptococcal pharyngeal infections), or tonsillitis.

NOW Oral Biotic lozenges can also help reduce halitosis (bad breath), when used in conjunction with proper oral hygiene. The lozenges have a natural strawberry and vanilla flavour.

This product has been reformulated by NOW Foods to contain half as much in each lozenge to make them easier to take, and to give more flexibility in the dosage, so children as young as 3 years old can take them (compared to no younger than 9 years, for certain other brands 1 Billion CFU doses).

Related Products: Also see BLIS Probiotics.

Latest product label differs slightly from the one shown.


Each OralBiotic lozenge contains:

21 mg (500 Million Colony Forming Units) of BLIS K12® Streptococcus salivarius

Other ingredients: FOS (Fructooligosaccharides), Xylitol, Sorbitol, Cellulose, Silica, Stearic Acid (vegetable source), Natural Flavours (Strawberry and Vanilla), Beet Powder (Beta vulgaris), Trehalose, and Lactitol.

Contains no salt, wheat, gluten, soy, egg, shellfish or preservatives.

BLIS = Bacteriocin-Like Inhibitory Substances

BLIS K12® are trademarks of BLIS Technologies Limited and subject of USA patent no. 7595041. The probiotic strain in this product has been identity-verified using DNA fingerprinting technology.

Suggested Usage:

Adults: Take 4 lozenges daily. Children 3 years and older: Take 1 to 2 lozenges daily.

To be effective, it is important that you allow each lozenge to dissolve slowly and completely in the mouth, rather than chewing it or swallowing it whole.

If you are taking antibiotics, do not take these lozenges at the same time as those: take them at least 2 to 3 hours either before or after taking the antibiotics.

Duration: To reduce halitosis, use for a minimum of 14 days, following use of an antimicrobial mouthwash.

Keep bottle refrigerated after opening to maintain live bacteria counts.


Allergen alert: Contains milk derivative.

Do not use NOW OralBiotic™ Probiotic Lozenges if you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment), or if you are taking aminoglycosidic antibiotics (e.g. kanamycin, streptomycin).

This product has come into contact with milk/dairy; do not use if you have a milk/dairy allergy.

Consult a healthcare practitioner prior to use if you have nausea, fever, vomiting, bloody diarrhea or severe abdominal pain. If symptoms of digestive upset (e.g. diarrhea) occur, worsen, or persist beyond three days, discontinue use and consult a healthcare practitioner.

Xylitol is harmful to pets; seek veterinary care immediately if you suspect they have ingested these lozenges (which are sweetened with that).

Health Canada Natural Product Number: 80112687.

Supporting Science:

The effectiveness of S. salivarius K12 in maintaining oral health has been evaluated in scores of clinical studies over the past two decades. Some of these, or reviews thereof, include:

"Effectiveness of the probiotic Streptococcus salivarius K12 for the treatment and/or prevention of sore throat: a systematic review." Clinical Microbiology and Infection, 2019.

"Evaluation of safety and human tolerance of the oral probiotic Streptococcus salivarius K12: A randomized, placebo-controlled, double-blind study." Food and Chemical Toxicology 2011.

"Extended Safety Data for the Oral Cavity Probiotic Streptococcus salivarius K12." Probiotics and Antimicrobial Proteins. 2010.

"Impact of Chlorhexidine Pretreatment Followed by Probiotic Streptococcus salivarius Strain K12 on Halitosis in Children: A Randomised Controlled Clinical Trial." Oral Health & Preventive Dentistry, 2016.

"Influence of Oral Probiotic Streptococcus salivarius K12 on Ear and Oral Cavity Health in Humans: Systematic Review." Probiotics and Antimicrobial Proteins, 2017.

"Positive clinical outcomes derived from using Streptococcus salivarius K12 to prevent streptococcal pharyngotonsillitis in children: a pilot investigation." Drug, Healthcare and Patient Safety, 2016.

"The rationale and potential for the reduction of oral malodour using Streptococcus salivarius probiotics." Oral Diseases, 2005.

UPC / Barcode: 733739829214