Info: Not Available in Canada
Provitalize is an American dietary supplement which purports to help menopausal or perimenopausal women lose weight and reduce symptoms such as hot flushes, bloating, sugar cravings, and joint pain. It is not currently available for sale in Canada.
While there is no single formula with all the same ingredients available here, we do have a number of products licensed by Heath Canada which can target those same symptoms – and perhaps more effectively.
Provitalize is marketed by Better Body Co. in the USA. We will post updates on a potential Canadian launch if and when details become available.
Provitalize is pitched primarily as a weight loss formula, which it chalks up primarily to its three probiotics, which have at least one published study each indicating that if you take them for at least a month (the trials range between 45 days and 12 weeks), they can either reduce a modest amount of existing body fat on their own even without changes in diet or exercise (the L.Gasseri (SBT 2055) strain), or boost the metabolism so you burn more calories rather than store them as fat (where they cite the B.Breve (IDCC 4401)), or improve BMI (the B.Lactis (R101-8)).
Although we do not have any products with those exact strains, we do have at least two clinically studied probiotics with comparable evidence and claims: Metagenic UltraFlora Control and Genestra HMF Metabolic Probiotic Formula.
Another facet of menopause Provitalize is designed to address is hot flashes and night sweats. The company's product page attributes its actions here mainly to the three probiotics (more on this below*) and to the moringa leaves, which also has some studies behind it in this area.
We do have several types of moringa on offer, including an Organic Moringa Powder by Nia Pure Nature.
There are also several kinds of other types of formulae available here which target hot flashes, including the medicinal mushroom oriented Menopause Relief (Hormone Rebalance) by Purica; a traditional herb, Black cohosh root, from St. Francis Herb Farm; and especially the specialized rhubarb extract Metagenics Estrovera, which actually comes with a money-back guarantee [pdf].
*(Regarding the alleged connection between probiotics and hormonal imbalances, others have explained it thus: a healthy balance of gut flora helps maintain a healthy metabolism, which does entail breaking down and recycling hormones in the body, which could theoretically help achieve hormonal balance by spurring the renewed production of the depleted ones. However, if that's the case, it could be true of any probiotics, particularly a multi-strain formula... and not only to the Provitalize blend, which is indeed a very strong daily dose but only of three strains.)
Provitalize also provides turmeric to help alleviate inflammatory symptoms like bloating, weight gain, and joint pain... along with a pinch of black pepper extract to make it more bioavailable (otherwise it's hard for the body to absorb).
This makes sense, here, since turmeric can be classified as a plant-based source of estrogen (a phytoestrogen) and there's a fair bit of evidence it can help on all these fronts (especially joint pain, where it's widely used to treat osteoarthritis and has been found to be better in relieving pain than NSAIDs) – even the mid-section. (E.g., apparently turmeric itself can alter the gut microbiome and improve intestinal barrier function, plus it can help improve bile flow to break down fats, which can reduce gas and bloating.)
We certainly have numerous types of either whole turmeric or extracts of its most active ingredient curcumin here, but the most suitable candidates might be ones that have been fermented (i.e., predigested by beneficial bacteria) first to make them easier to digest and more effective: Organic Fermented Turmeric Powder, by Prairie Naturals, and especially Living Alchem Turmeric Alive, which also includes Ginger, another phytoestrogen, which can also help with digestion and relieve both nausea and bloating.
There's also one other major ingredient in Provitalize, Curry Leaf Extract, which they say might be able to help with cholesterol, blood sugar levels, and indigestion. At first blush, it's unclear what those have to do weight loss or menopause, but if you are concerned about those things, we have a whole collection of natural health products that do address cholesterol, blood sugar, and digestive issues – just not with that particular ingredient, which is just as well, since scientific literature reviews continue to show there's a distinct lack of evidence for it.
Finally, a graphic on the manufacturer's site for this product says it can reduce sugar cravings, but they don't say how / which ingredient might be responsible for that, so it is difficult to evaluate this claim. However, if that is something you would like help with, we would recommend Gymnema Sylvestre.
Each 2 Capsule Daily Serving contains:
400 mg Probiotic Blend, providing a total of 68.2 Billion Colony Forming Units, of a proprietary blend of B.Breve (IDCC 4401), B.Lactis (R101-8), and L.Gasseri (SBT 2055)
350 mg Turmeric Root Extract (standardized to 95% Curcuminoids)
350 mg Moringa Leaf (Moringa oleifera)
150 mg Curry Leaf (Helichrysum italicum)
50 mg Lecithin (from Sunflower)
3 mg Black Pepper Fruit Extract (BioPerine)
Adults: Take two capsules daily first thing in the morning, either with or without food.
Provitalize Side Effects & Warnings:
Keep out of reach of children. Consult your healthcare professional before using, especially if you are pregnant or nursing or have a medical condition.
Provitalize's Citations Regarding its Own 3 Probiotics
Bernini, LJ et al. “Beneficial effects of Bifidobacterium lactis on lipid profile and cytokines in patients with metabolic syndrome: a randomized trial.” Nutrition, 2015.
Kadooka, Y et al. “Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial.” European Journal of Clinical Nutrition, 2010.
Minami, Jun-Ichi et al. “Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial.” Journal of Nutritional Science, 2015.
Regarding Turmeric and Curcumin
Boonjaraspinyo, Sirintip et al. “Indirect effect of a turmeric diet: enhanced bile duct proliferation in Syrian hamsters with a combination of partial obstruction by Opisthorchis viverrini infection and inflammation by N-nitrosodimethylamine administration.” Parasitology Research, 2011.
Marciani, L et al. “Effects of various food ingredients on gall bladder emptying.” European Journal of Clinical Nutrition, 2013.
Hsiao, An-Fang et al. “The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis.” Complementary Therapies in Medicine, 2021.
Koroljević, ZD et al. “Curcuma as an anti-inflammatory component in treating osteoarthritis.” Rheumatology International, 2023.
Peterson, Christine T et al. “Effects of Turmeric and Curcumin Dietary Supplementation on Human Gut Microbiota: A Double-Blind, Randomized, Placebo-Controlled Pilot Study.” Journal of Evidence-based Integrative Medicine 2018.
Pluta, Ryszard et al. “Mutual Two-Way Interactions of Curcumin and Gut Microbiota.” International Journal of Molecular Sciences, 2020.
Scazzocchio, Beatrice et al. “Interaction between Gut Microbiota and Curcumin: A New Key of Understanding for the Health Effects of Curcumin.” Nutrients, 2020.
Regarding the Lack of Evidence from Human Trials on Helichrysum italicum
Antunes Viegas, Daniel et al. “Helichrysum italicum: from traditional use to scientific data.” Journal of Ethnopharmacology, 2014.
Furlan, Veronika, and Urban Bren. “Helichrysum italicum: From Extraction, Distillation, and Encapsulation Techniques to Beneficial Health Effects.” Foods (Basel, Switzerland), 2023.
Kramberger, Katja et al. “A Review and Evaluation of the Data Supporting Internal Use of Helichrysum italicum.” Plants (Basel, Switzerland), 2021.