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DeVita Vite - Neural Revive (Harp Seal Oil)

DeVita Vite - Neural Revive (Harp Seal Oil)

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Info: 150 ml Bottle; Natural Lemon Flavour

Harp Seal Oil is likely the most complete source of Omega-3's to be found in nature, whose high DPA (docosapentanoic acid) content not only enables it to do everything conventional fish oils do (like reduce inflammation, and help the skin) – only better, and without a fishy taste! Seal oil has also been shown to help regenerate damaged blood vessels and nerves, making it especially well-suited for those with peripheral neuropathy.

Info: 150 ml Bottle; Natural Lemon Flavour

Harp Seal Oil is likely the most complete source of Omega-3's to be found in nature, whose high DPA (docosapentanoic acid) content not only enables it to do everything conventional fish oils do (like reduce inflammation, and help the skin) – only better, and without a fishy taste! Seal oil has also been shown to help regenerate damaged blood vessels and nerves, making it especially well-suited for those with peripheral neuropathy.

Product Notes:

Seals are of course mammals who eat a lot of fish, and like us, their metabolic and digestive systems can filter out many of the impurities in what they eat. That "bio-filtering" produces a lesser-known Omega-3 essential fatty acid called DPA (which has two main variants or isomers; the one found in seal oil [n-3 DPA] is also known as clupanodonic acid).

DPA is not found in significant amounts in most fish oils (which mostly contain only DHA and EPA as Omega-3s), although it also can be found in lesser amounts in human breast milk and in grass-fed beef.

Previous studies have indicated that DPA enhances the health benefits of DHA and EPA for cardiovascular protection in various ways, such as by reducing the risk of blood clots and plaque build-up in arteries, lowering plasma triglycerides and blood pressure in those with too many fats in their blood; and reducing inflammation.  And newer research has shown that it can not only able to help improve the fluidity / flow of blood within blood vessels but can also help protect and even regenerate nerves, and thus slow or even reverse the progress of peripheral neuropathy.

Peripheral neuropathy (which usually manifests in stages as numbness, tingling, pain, and then an almost total loss of sensation (including for hot and cold) in the hands and feet, for the damaged sensory nerves; or as twitches, cramps, and muscle weakness and loss when it's the motor nerves that are damaged) can be caused not only by high blood sugar levels (both diabetics and pre-diabetics are at risk), but also by chemotherapy, alcohol, and certain heavy metals (which this seal oil has been purified to be free of). Left unchecked, it can result in sores and injuries that lead to infections and even amputations. ;

Apart from the sensible lifestyle guidance (to curtail sugar and alcohol intake and increase exercise, to at least slow its progression), the usual medical treatment for neuropathy is to prescribe medications to dampen the painful or distracting symptoms such as stabbing or electric shock-style pains, or itching or "pins and needles" or burning or coldness sensations. However, that only masks the symptoms of the problem; as outlined by the developer of this product, "Neuropathy can only be stopped by rebuilding damaged nerves".

Neural Revive was developed by Dr. Evan Lewis, who has a PhD from the Department of Nutritional Sciences in the Faculty of Medicine at the University of Toronto, and has received funding from the Canadian Institute for Health Research, the Banting & Best Diabetes Centre, and the Canadian Diabetes Association to pursue his research in this area. 

To demonstrate that DPA-rich harp seal oil can in fact rebuild damaged nerves in people with diabetes, Dr. Lewis and his colleagues conducted a year-long clinical study using a minimally invasive imaging method. Rather than extracting a series of skin punch biopsies to detect the density of small nerve fibres there in order to compare treatment groups (which is problematic for people already prone to slow-healing skin wounds), they used a body part where the nerves can actually be visualized without removing any tissue: the eyeball!

In brief, they simply pressed a microscope right up to a subject's (locally anesthetized) cornea, and added up the total length of all the corneal nerve fibres that could be seen in a given area on a given date (they look like little streams as seen from a satellite), and recorded how much that changed (either every four months, for the 1-year seal oil treatment group, or every year, for a baseline group they were compared to).

To establish the baseline of what to expect in that area from the regular course of progression for diabetics, they drew on previous research by Ahmed et al. which compiled six years of data on non-diabetic 'controls' and diabetics at various stages of neuropathy who were not using any seal oil treatment, and found pretty much no change in the corneal nerve fibre length (CNFL) from year to year for the control group, and decreases of about 1% a year for diabetics with a stable condition and a 6% annual decrease among those with unstable (also called labile or brittle diabetes, where the blood glucose levels often swing from very low [hypoglycemic] to very high [hyperglycemic]).

Then, for the 1-year clinical trial of 40 subjects with Type 1 diabetes (simply because their institution already had good access to a pool of Type 1 diabetics; they are confident from previous studies on the normal course of neuropathy that the results would apply equally to those with Type 2) and various degrees of neuropathy, Evans et al. measured their corneal nerve fibre lengths at the start of the study and every four months after beginning to take 10 ml of this harp seal oil daily. And for the 32 who stuck it out for the whole year, they found an average 29% INCREASE, rather than the expected 1 to 6% decrease in CNFL (with the greatest changes in those who were the worst off to begin with).

Of course, this proof-of-concept experimental trial doesn't mean diabetics should expect seal can only help regenerate nerves within the eyeball: that was just the place where it was most convenient to look. As Evans explains here and elsewhere there are a number of reasons this complete source of Omega 3's should help reverse neuropathy in the extremities especially when that's due to diabetes, including the facts that nerves themselves are partly composed of Omega 3's; diabetics do not metabolize them as well as other people, and so tend to have lower levels of them and excessive levels of inflammation-inducing Omega 6's (which are more prevalent in our diets) circulating in the blood; and consuming seal oil can greatly improve that circulating Omega 6 to Omega 3 ratio, and improve vascular function (specifically, its membrane fluidity or biodynamics), especially when taken sublingually (held in the mouth for a while before swallowing, since there's an enzyme in our mouth called lingual lipase which enables us to break down certain fats and absorb them into our bloodstream very quickly and efficiently.  


Each 5 ml (1 tsp) dose contains:

2,777 mg Harp Seal Oil (Pagophilus groenlandicus), providing:
1000 mg Total Omega-3s*, including:
- 300 mg EPA (Eicosapentaenoic acid)
- 150 mg DPA (Docosapentaenoic acid)
- 400 mg DHA (Docosahexaenoic acid)

Non-medicinal ingredients: Natural lemon flavour, Medium chain triglycerides (MCTs), and Vitamin E (as an antioxidant/preservative).

This seal oil has been produced in Canada from an abundant and sustainable population of wild caught seals, using a unique manufacturing process to remove heavy metals and toxins to produce a pharmaceutical grade product. 

In addition to those total Omega-3's, some other constituents of Harp Seal blubber (and thus oil) in the remaining content include:
- 3-Deoxyvitamin D3 (vitamin D3)
- Arachidonic acid (an omega-6 polyunsaturated fatty acid our bodies can use to produce the pleasure/contentment molecule, AEA [anandamide])
- Cetoleic acid (an omega-11 polyunsaturated fatty acid)
- Eicosadienoic acid (an omega-6 polyunsaturated fatty acid)
- Glycerolipid (2 types of glycosyldiacylglycerols, which serve as constituents of many cell membranes)
- Hypogeic Acid (an unsaturated omega-9 long chain fatty acid that's also found in human milk)
- Linoleic acid (an omega-6 polyunsaturated fatty acid)
- Myristic acid (a long-chain saturated fatty acid, that's also the most prevalent type of milk fat)
- Myristoleic acid (an omega-5 monounsaturated fatty acid)
- Oleic acid (an omega-9 unsaturated fatty acid, that's also found in mother's milk)
- Palmitoleic acid (an omega-7 monounsaturated fatty acid)
- Phenolic phthiocerol (a lipid used by the immune system to transport antigens or antibodies)
- Squalene (an omega-2 unsaturated fatty acid)

Suggested Usage:

Adults: For a preventive or maintenance dose, take 5 ml (1 teaspoon) once a day, shortly before eating. If you are already experiencing symptoms of neuropathy, for a therapeutic dose (which is apt to take at least to 12 weeks before achieving noticeable results for those with mild symptoms, or 6 to 9 months for those with more advanced symptoms), take it twice a day, for a total of 10 mL (2 tsp) per day.

For optimal absorption, use the sublingual method: hold it under your tongue for at least a minute before swallowing, to capitalize on humans' 'hard-wired' ability to quickly and efficiently absorb certain fats that are also in breast milk, that way.

Keep bottle lid tightly closed, away from heat, and refrigerate after opening.


No known Contraindications, Adverse reactions, or Cautions and Warnings statements required.

Health Canada Natural Product Number: 80076725. This product was originally licensed by Nutarniq Corp. and is also marketed under other names, including theirs: Frontline Neuropathy. Neural Revive is a new product developed by (DV) DeVita Vite, which is affiliated with Biotics Research Canada.

Supporting Science:

Ahmed, Ausma et al. “Detection of diabetic sensorimotor polyneuropathy by corneal confocal microscopy in type 1 diabetes: a concurrent validity study.” Diabetes Care, 2012.

Britten-Jones, Alexis Ceecee et al. “Investigating the Neuroprotective Effect of Oral Omega-3 Fatty Acid Supplementation in Type 1 Diabetes (nPROOFS1): A Randomized Placebo-Controlled Trial.” Diabetes, 2021.

Dong, Ye et al. “Docosapentaenoic Acid (DPA, 22:5n-3) Alleviates Ulcerative Colitis via Modification of Gut Microbiota and Their Metabolism.” Nutrients, 2022.

Lewis, Evan JH et al. “Effect of omega-3 supplementation on neuropathy in type 1 diabetes: A 12-month pilot trial.” Neurology, 2017.

Lewis, Evan JH et al. “Baseline omega-3 level is associated with nerve regeneration following 12-months of omega-3 nutrition therapy in patients with type 1 diabetes.” Journal of Diabetes and its Complications, 2021.

Meyer, Barbara J et al. “Comparison of seal oil to tuna oil on plasma lipid levels and blood pressure in hypertriglyceridaemic subjects.” Lipids, 2009.

Pinedo, Megahn H. et al. “Oil Identification of harp seal and other select marine mammals.” Forensic Science International: Animals and Environments, 2024.

Tikhonenko, Maria et al. “N-3 polyunsaturated Fatty acids prevent diabetic retinopathy by inhibition of retinal vascular damage and enhanced endothelial progenitor cell reparative function.” PloS one, 2013.

UPC / Barcode: 030034706104