Info: Not Currently Available in Canada
Urolithin A is a natural postbiotic compound (produced by beneficial bacteria during the course of fermentation*) that promotes mitochondrial function (the parts of our cells which produce usable energy from food, among other things) and mitophagy (the selective recycling of those mitochondria).
Sold in some markets under the trade name "Mitopure," it has been the subject of a rapidly increasing number of studies indicating it improves muscle strength and has a beneficial impact on certain biomarkers of cellular health, particularly in middle-aged and older people, and is thus heralded as an anti-aging product.
Urolithin A has yet to be issued a Natural Product Number to be licensed to sell as a natural health product in Canada. We'll be sure to provide additional information on a potential Canadian launch as soon as it's available.
* In this case, the fermentation to produce Urolithin A (UA) is achieved by using gut-derived bacteria to consume foods which contain ellagitannin, such as pomegranate, strawberry, raspberry, blackberry, muscadine grapes, or walnuts.
Other supplements found to influence mitophagy and mitochondrial function that are available in Canada include:
NMN+ Wheat Germ (Nicotinamide Mononucleotide & Spermidine), from AOR;
Glycine + NAC (GlyNAC), from NOW; and,
RegenerLife Mitochondrial Energy Formula, from Natural Factors.
There is also a licensed natural health product specifically designed to help reverse natural muscle loss: MuscleRescue (Reginator), from Innovite.
Mitopure™ is a trademark of Amazentis SA in the USA.
D'Amico, Davide et al. “Impact of the Natural Compound Urolithin A on Health, Disease, and Aging.” Trends in Molecular Medicine, 2021.
Kothe, Breanne et al. “Urolithin A as a Potential Agent for Prevention of Age-Related Disease: A Scoping Review.” Cureus, 2023.
Singh, Anurag et al. “Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults.” Cell Reports. Medicine, 2022.